If Python is included in your hosting package, you will see the Python logo in the domain overview of your Plesk panel. The Python integration is carried out via a passenger server with a WSGI interface. Your applications must be specially written for WSGI (How to).
Available options in your Plesk panel:
Switch on: Activates the Python support for the corresponding domain
Disable: Deactivates the Python support for the corresponding domain
Rewrite Config: Changes to the settings are applied (slowly)
Application Reload: Application server is restarted (fast)
Note: Changed settings are applied only after switching on again. Clicking on Application Reload creates the file restart.txt in the App Root's /tmp directory. The Passenger Server will then reload the application.
Settings:
App Root: The root directory of the application is specified here; it is relative to the web space and should not be in the Document Root for security reasons.
Startup File: Your application starts running with this file
Python Version: The currently available Python versions are displayed here
Mode: Productive = no error messages are shown, development = error messages are shown